https://www.deepikavasudevan.info/contact-me daily 0.75 2024-06-18 https://www.deepikavasudevan.info/education-1 daily 0.75 2020-01-14 https://www.deepikavasudevan.info/mentoring daily 0.75 2024-06-18 https://www.deepikavasudevan.info/about-me daily 1.0 2024-06-18 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/a23fabf8-239e-42c0-bc1a-19073bb763e5/2023-photo.jpg ABOUT ME https://www.deepikavasudevan.info/research-n daily 0.75 2024-06-18 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578690345113-QUZE1H9YAKWOCIZNIM17/Fucosylation-protein-folding Research https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578691820626-K7NYAF4D21Q4V9IWEXH3/RetinalDegeneration.png Research https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578690731569-8WMTWCX81Z1MLWG6OV97/Thor2p-dsRed-screen Research https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578943755272-1WVIJ6SL0EQKRDU696TF/eye+ablation Research https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578690373392-WXETOFCVFGKDRXAV928Q/B3GLCT-targets Research https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578688922356-AAHX3XEBPV5M3UX77OSY/4E-BP_innate+immunity Research https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578688871664-7K8L6D2I23ZYRTM1491M/4-2.png Research https://www.deepikavasudevan.info/reporters daily 0.75 2020-01-13 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578697679699-9K4Y4YA02OJ9TXOP3BC5/4-1.png Reporters Stress response signaling and it’s downstream effects on mRNA translation. https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578697679638-3PHIY8ZD5ZTBD72LAC34/4-2.png Reporters Expression of the 4E-BP-intron-DsRed reporter in adult flies after overnight starvation (fed water only). https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578700887008-ZRDYTU99CTUXC81DYTQH/4-3.png Reporters The 4E-BP-intron-DsRed reporter shows that many tissues in the fly experiences during development. https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578700886789-MPQ9K1M9CNTAP527RMZY/4-4.png Reporters Expression of 4E-BP-intron-DsRed, 4E-BP-intron_mutant-DsRed and 4E-BP-upstream-DsRed at the wandering third instar larval stage. https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701377987-2IMY9ECG8KHPE5F995WN/4-6.png Reporters Vector map of the pBC plasmid. https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701076014-ZRV3ANG83CF0IMD6Q8MR/4-5.png Reporters Schematic of the in vivo mono cistronic Drosomycin-GFP reporters (DromP-Drom-GFP, DromP-Tub-GFP). https://www.deepikavasudevan.info/immunity daily 0.75 2021-02-24 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701567956-OONJFZUMT1SL498RNQQP/5-1.png Immunity Enteric infection in Drosophila activates cellular stress response in the fat tissues where stress drives anti-microbial peptide translation. https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701624734-S1S2OBAVINCJ886RGZ0L/5-2.png Immunity CFUs from a pathogen load assay using Ecc15 (Erwinia carotovora carotovora 15) as a pathogen to enterically infect 2nd instar Drosophila larva. https://www.deepikavasudevan.info/initiation daily 0.75 2021-06-18 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701773781-8UZ43F1A05EXWKDI5MLN/6.png Initiation 4E-BP-intron-DsRed used as a platform to screen for new regulators of the stress response. https://www.deepikavasudevan.info/adrp daily 0.75 2021-02-24 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701905488-48SCZVIQV21Z497RV1ZM/7-1.png Autosomal Dominant Retinitis Pigmentosa Monitoring the health of adult fly eyes during aging using photoreceptors marked with a fluorescent Rhodopsin (Rh1-RFP). https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701905403-O1QVA2TP9MVPWPTCD455/7-2.png Autosomal Dominant Retinitis Pigmentosa https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578701906114-M9ZZGASKTVH466TGODG2/7-3.png Autosomal Dominant Retinitis Pigmentosa https://www.deepikavasudevan.info/degenerative daily 0.75 2021-02-24 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578943482010-HNA6W4HLCB1OYVRJPP55/Eye_ablation Degenerative role of stress Eye ablation in young flies as seen in a chronic stress model where misfolded protein is overexpressed in the eye. https://www.deepikavasudevan.info/folding daily 0.75 2020-01-13 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578696857077-SN3WSJ5303KJA8NLIERI/O-glycosylation+in+protein+folding O-glycosylation in folding Model for how fucoslyation and subsequent glucosylation by POFUT2 and B3GLCT drives TSR folding, https://www.deepikavasudevan.info/pps daily 0.75 2020-01-13 https://images.squarespace-cdn.com/content/v1/5e1254c7977d182367a25189/1578696643243-OZF7KRDBI8GNZLLROSX5/TSR-mass+spec Peters plus syndrome Mass spectrometry traces of unique di-, mono-, or unglycosylated peptides from TSR domains in ADAMTS9. (red triangle = fucose, blue circle = glucose).